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Professorship Microbial Biotechnology

The professorship for Microbial Biotechnology at the TUM Campus Straubing for Biotechnology and Sustainability was established in October 2018 and is headed by Prof. Dr. Bastian Blombach.

We focus on the development and optimization of microbial production processes for chemicals and fuels from renewable resources and systems-level physiological studies of microbes under industrial process conditions. To achieve this goal, we apply the methodology of metabolic engineering, systems biology and synthetic biology to exploit the potential of established and novel microbial systems for industrial biotechnology. The construction of tailor-made cell factories is carried out by modern methods of genetic engineering and is supported by metabolome analyzes. The development of a quantitative and systemic understanding of the metabolic performance of microbial platforms such as Vibrio natriegens, Pseudomonas putida, Hydrogenophaga pseudoflava and Corynebacterium glutamicum is essential in this context. In addition, we are investigating metabolic networks of the model plant Arabidopsis thaliana in particular with respect to the functions of cytochrome P450 enzymes and their application in microbial biotechnology.


Professorship Microbial Biotechnology

Uferstraße 53
D-94315 Straubing


Prof. Dr. Bastian Blombach

Phone: +49 (0) 9421 187-420

Team Assistant

Nancy Stüpfert

Phone: +49 (0) 9421 187-425


Aktuelle Publikationen

Thoma, F., A. Appel, D. Russ, J. Huber, F. Werner, and B. Blombach. 2023. Improving growth properties of Corynebacterium glutamicum by implementing an iron-responsive protocatechuate biosynthesis. Microb. Biotechnol. DOI: 10.1111/1751-7915.14244.

Schmollack, M., F. Werner, J. Huber, D. Kiefer, M. Merkel, R. Hausmann, D. Siebert, and B. Blombach. 2022. Metabolic engineering of Corynebacterium glutamicum for acetate-based itaconic acid production. Biotechnol Biofuels Bioprod. 15:139.

Bharti, R., D. Siebert, B. Blombach, and Dominik G. Grimm. 2022. Systematic analysis of the underlying genomic architecture for transcriptional-translational coupling in prokaryotes. NAR Genom. Bioinform. 4:lqac074.

Siebert, D., B. J. Eikmanns, and B. Blombach. 2022. Exploiting aerobic carboxydotrophic bacteria for industrial biotechnology. Adv. Biochem. Eng. Biotechnol. 180:1-32.

Thoma, F., C. Schulze, C. Gutierrez-Coto, M. Hädrich, J. Huber, C. Gunkel, R. Thoma, and B. Blombach. 2022. Metabolic engineering of Vibrio natriegens for anaerobic succinate production. Microb. Biotechnol. 15:1671-1684.





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