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Gruppenleiter

Apl. Prof. Dr. Erich Glawischnig
Apl. Prof. Dr. Erich Glawischnig

Gruppenleiter

Tel.: +49 (0) 9421 187-424
E-Mail: glawischnig@tum.de

TUM Campus Straubing
Uferstraße 53
94315 Straubing

Uferstraße 53 Raum: 02.3505.133

Vita

 

Lebenslauf

  • seit 2018 Gruppenleiter an der Professur Mikrobielle Biotechnologie
  • 2017-2018 Wissenschaftlicher Mitarbeiter und Dozent am Lehrstuhl für Chemie Biogener Rohstoffe.
  • Verantwortlicher für Staatsexamina Lehramt Biologie im Bereich Botanik (2016/2017)
  • Bestellung zum außerplanmäßigen Professor (2015)
  • 2012-2017 DFG Heisenbergstipendiat (TUM, WZW)
  • Habilitation und Ernennung zum Privatdozenten (2007)
  • 2002-2012 Arbeitsgruppenleiter am Lehrstuhl für Genetik (TUM)
  • 2000-2002 EMBO-stipendiat am Zentrum für Molekulare Pflanzenphysiologie (Halkier Lab), Kopenhagen, Dänemark
  • Hans-Fischer-Gedächtnispreis (1998)
  • Promotion bei Prof. Gierl zum Thema ”Biochemische und genetische Aufklärung der Biosynthese von Benzoxazinonen in Zea mays” (mit Auszeichnung, 1997)
  • 1994-2000 Wissenschaftlicher Mitarbeiter am Lehrstuhl für Genetik (TUM)
  • 1987-1993 Studium der Biologie (Diplom), Hauptfach Mikrobiologie (TU München)

Forschung

  • Pflanzlicher Tryptophanstoffwechsel, insbesondere Biosynthese Pathogen-induzierter Abwehrstoffe
  • Pflanzliche Cytochrom P450-Enzmye

Publikationen

2020
  • Durian G, Jeschke V, Rahikainen M, Vuorinen K, Gollan PJ, Brosché M, Salojärvi J, Glawischnig E, Winter Z, Li S, Noctor G, Aro EM, Kangasjärvi J, Overmyer K, Burow M, Kangasjärvi S. (2020) PROTEIN PHOSPHATASE 2A-B’γ controls Botrytis cinerea resistance and developmental leaf senescence.Plant Physiol. 182(2):1161-1181.

2019

  • Mucha S, Heinzlmeir S, Kriechbaumer V, Strickland B, Kirchhelle C, Choudhary M, Kowalski N, Eichmann R, Hückelhoven R, Grill E, Kuster B, Glawischnig E. (2019) The formation of a camalexin-biosynthetic metabolon. Plant Cell, 31: 2697-2710.
  • Pastorczyk M, Kosaka A, Piślewska-Bednarek M, López G, Frerigmann H, Kułak K, Glawischnig E, Molina A, Takano Y, Bednarek P. (2019) The role of CYP71A12 monooxygenase in pathogen-triggered tryptophan metabolism and Arabidopsis immunity. New Phytol. doi: 10.1111/nph.16118. [Epub ahead of print]
  • Müller T, Böttcher C, Glawischnig E. (2019) Dissection of the network of indolic defence compounds in Arabidopsis thaliana by multiple mutant analysis. Phytochemistry, 161:11-20.

2018

  • Mayer D, Mithöfer A, Glawischnig E, Georgii E, Ghirardo A, Kanawati B, Schmitt-Kopplin P, Schnitzler JP, Durner J, Gaupels F. (2018) Short-term exposure to nitrogen dioxide provides basal pathogen resistance. Plant Physiol. 178(1):468-487

2017

  • Rahikainen M, Trotta A, Alegre S, Pascual J, Vuorinen K, Overmyer K, Moffatt B, Ravanel, S, Glawischnig E, Kangasjärvi S (2017). PP2A-B’γ modulates foliar trans-methylation capacity and formation of 4-methoxy-indol-3-yl-methyl glucosinolate in Arabidopsis leaves. Plant Journal, 89(1):112-127.

2016

  • Frerigmann H, Piślewska-Bednarek M, Sánchez-Vallet A, Molina A, Glawischnig E, Gigolashvili T, Bednarek P. (2016) Regulation of pathogen triggered tryptophan metabolism in Arabidopsis thaliana by MYB transcription factors, Molecular Plant, 9(5):682-95.
  • Chapman A, Lindermayr C, Glawischnig E. (2016) Expression of antimicrobial peptides under control of a camalexin-biosynthetic promoter confers enhanced resistance against Pseudomonas syringae. Phytochemistry, 122:76-80.

2015

  • Frerigmann H, Glawischnig E, Gigolashvili T (2015) The role of MYB34, MYB51 and MYB122 in the regulation of camalexin. Frontiers in Plant Science, 6:654.
  • Peskan-Berghöfer T, Vilches-Barro A., Müller TM, Glawischnig E, Reichelt M, Gershenzon J, Rausch T (2015). Sustained exposure to ABA enhances colonization potential of the mutualist fungus Piriformospora indica on Arabidopsis thaliana roots. New Phytologist, 208, 873-886.
  • Müller TM, Böttcher C, Morbitzer R, Götz CC, Lehmann J, Lahaye T, Glawischnig E (2015) TALEN-mediated generation and metabolic analysis of camalexin-deficient cyp71a12 cyp71a13 double knockout lines. Plant Physiology 168: 849-858.
  • Mucha S, Walther D, Müller T, Hincha DK, Glawischnig E (2015) Substantial reprogramming of the Thellungiella salsuginea transcriptome in response to UV and silver nitrate challenge. BMC Plant Biol 15:137

2014

  • Böttcher C, Chapman A, Fellermeier F, Choudhary M, Scheel D, Glawischnig E (2014) The biosynthetic pathway of indole-3-carbaldehyde and indole-3-carboxylic acid derivatives in Arabidopsis thaliana. Plant Physiology 165(2):841-853.

2013

  • Weis C, Pfeilmeier S, Glawischnig E, Isono E, Pachl F, Hahne H, Küster B, Eichmann R, Hückelhoven R (2013) Co-immunoprecipitation-based identification of putative BAX INHIBITOR-1-interacting proteins involved in cell death regulation and plant – powdery mildew interactions. Mol Plant Pathol. 14(8):791-802.

2012

  • Mewis I, Khan MAM, Glawischnig E, Schreiner M, Ulrichs C. (2012) Water Stress Mediated Alteration in Plant Response of Arabidopsis thaliana (L.) to Aphid Feeding. PLoS ONE, 7(11):e48661.
  • Nongbri PL, Johnson JM, Sherameti I, Glawischnig E, Halkier BA, Oelmüller R. (2012) Indole-3-acetaldoxime derived compounds restrict root colonization in the beneficial interaction between Arabidopsis roots and the endophyte Piriformospora indica. Mol Plant Microbe Interact, 25, 1186-1197

2011

  • Pedras MS, Yaya E, Glawischnig E. (2011) The phytoalexins from cultivated and wild crucifers: Chemistry and biology. Nat Prod Rep, 28, 1381-1405

2010

  • Yin R, Frey M, Gierl A, Glawischnig E. (2010) Plants contain two distinct classes of functional tryptophan synthase beta proteins. Phytochemistry, 71, 1667-1672

2009

  • Böttcher C, Westphal L, Schmotz C, Prade E, Scheel D, Glawischnig E. (2009) The multifunctional enzyme, CYP71B15 (PHYTOALEXIN DEFICIENT 3), converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana. Plant Cell, 21, 1830-1845
  • Rauhut T, Glawischnig E. (2009) Evolution of camalexin and structurally related indolic compounds. Phytochemistry, 70, 1638-1644
  • Rauhut T, Luberacki B, Seitz HU, Glawischnig E. (2009) Inducible expression of a Nep1-like protein serves as a model trigger system of camalexin biosynthesis. Phytochemistry, 70, 185-189

2008

  • Kriechbaumer V, Weigang L, Fießelmann A, Letzel T, Frey M, Gierl A, Glawischnig E. (2008) Characterisation of the tryptophan synthase alpha subunit in maize. BMC Plant Biology, 8, 44
  • Rauhut T, Spiteller P, Eisenreich W, Spiteller M, Glawischnig E. (2008) The biosynthetic origin of BE-10988 in Streptomyces spec. BA10988. J Org Chem, 73, 5279-5286
  • Siemens J, Glawischnig E, Ludwig-Müller J. (2008) Indole glucosinolates and camalexin do not influence the development of the clubroot disease in Arabidopsis thaliana. J Phytopathology, 156, 322-337

2007

  • Kriechbaumer V, Park WJ, Piotrowski M, Meeley RB, Gierl A, Glawischnig E. (2007) Maize nitrilases have a dual role in auxin homeostasis and b-cyanoalanine hydrolysis. J Exp Botany, 58, 4225-4233
  • Gust AA, Biswas R, Lenz HD, Rauhut T, Ranf S, Kemmerling B, Götz F, Glawischnig E, Lee J, Felix G, Nürnberger T. (2007) Bacteria-derived peptidoglycans constitute pathogen-associated molecular patterns triggering innate immunity in Arabidopsis. J Biol Chem, 282, 32338-32348
  • Nafisi M, Goregaoker S, Botanga CJ, Glawischnig E, Olsen CE, Halkier BA, Glazebrook J 2007). Arabidopsis cytochrome P450 monooxygenase 71A13 catalyzes the conversion of indole-3-acetaldoxime in camalexin synthesis. Plant Cell, 19, 2039-2052
  • Glawischnig E. (2007) Camalexin. Phytochemistry, 68, 401-406
  • Schuhegger R, Rauhut T, Glawischnig E. (2007) Regulatory variability of camalexin biosynthesis. J Plant Physiology, 164, 636-644

2006

  • Qutob D, Kemmerling B, Brunner F, Küfner I, Engelhardt S, Gust AA, Luberacki B, Seitz H-U, Stahl D, Rauhut T, Glawischnig E, Schween G, Lacombe B, Watanabe N, Lam E, Schlichting R, Scheel D, Nau K, Dodt G, Hubert D, Gijzen M, Nürnberger T. (2006) Phytotoxicity and innate immune responses induced by Nep1-like proteins. Plant Cell, 12, 3721-3744
  • Schuhegger R, Nafisi M, Mansourova M, Petersen BL, Olsen CE, Svatos A, Halkier BA, Glawischnig E. (2006) CYP71B15 (PAD3) catalyzes the final step in camalexin biosynthesis. Plant Physiology, 141, 1248-1254
  • Glawischnig E. (2006) The role of cytochrome P450 enzymes in the biosynthesis of camalexin. Biochem Soc Transactions, 34,1206-1208
  • Kriechbaumer V, Park WJ, Gierl A, Glawischnig E. (2006) Auxin biosynthesis in maize. Plant Biology, 8, 334-339

2005

  • Kriechbaumer V, Glawischnig E. (2005) Auxin biosynthesis within the network of tryptophan metabolism. JNBT, 2, 55-58
  • Treml B, Winderl S, Radykewicz R, Herz M, Schweizer G, Hutzler P, Glawischnig E, Torres Ruiz RA. (2005) The gene ENHANCER OF PINOID controls cotyledon development in the Arabidopsis embryo. Development, 132, 4063-4074

2004

  • Glawischnig E, Hansen BG, Olsen CE, Halkier BA. (2004) Camalexin is synthesized from indole-3-acetaldoxime, a key branching point between primary and secondary metabolism in Arabidopsis. Proc Natl Acad Sci USA, 101, 8245-8250
  • Adelsberger H, Hertel C, Glawischnig E, Zverlov VV, Schwarz WH. (2004) Enzyme system of Clostridium stercorarium for hydrolysis of arabinoxylan: reconstitution of the in vivo system from recombinant enzymes. Microbiology, 150, 2257-2266

2003

  • Park WJ, Kriechbaumer V, Müller A, Piotrowski M, Meeley RB, Gierl A, Glawischnig E. (2003) The nitrilase ZmNIT2 converts indole-3-acetonitrile to indole-3-acetic acid. Plant Physiology, 133, 794-802
  • Glawischnig E, Mikkelsen MD, Halkier BA. (2003) Glucosinolate biosynthesis and metabolism. In Abrol Y., Altaf A. (Eds.) Sulphur in Higher Plants. Kluwer Academic Publishers, Dordrecht, NL
  • Chen S, Glawischnig E, Jørgensen K, Naur P, Jørgensen B, Olsen C-E, Hansen CH, Rasmussen H, Pickett JA, Halkier BA. (2003) CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis. Plant Journal, 33, 923-937
  • Mikkelsen MD, Petersen BL, Glawischnig E, Andreasson E, Jensen AB, Halkier BA. (2003) Modulation of CYP79 genes and glucosinolate profiles in Arabidopsis by defense signaling pathways. Plant Physiology, 131, 298-308

2002

  • Glawischnig E, Gierl A, Tomas A, Bacher A, Eisenreich W. (2002) Starch biosynthesis and intermediary metabolism in maize kernels. Quantitative analysis of metabolite flux by NMR. Plant Physiology, 130, 1717-1727

2001

  • Spiteller P, Glawischnig E, Gierl A, Steglich W. (2001) Studies on the biosynthesis of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) from 3-hydroxyindolin-2-one in Zea mays. Phytochemistry, 57, 373-376
  • Glawischnig E, Gierl A, Tomas A, Bacher A, Eisenreich W. (2001) Retrobiosynthetic nuclear magnetic resonance analysis of amino acid biosynthesis and intermediary metabolism. Metabolic flux in developing maize kernels. Plant Physiology, 125, 1178-1186

2000

  • Glawischnig E, Tomas A, Eisenreich W, Spiteller P, Bacher A, Gierl A. (2000) Auxin biosynthesis in maize kernels. Plant Physiology, 123, 1109-1119

1999

  • Glawischnig E, Grün S, Frey M, Gierl A. (1999) Cytochrome P450 mono-oxygenases of DIBOA biosynthesis: Specificity and conservation among grasses. Phytochemistry, 50, 925-930

1997

  • Glawischnig E, Eisenreich W, Bacher A, Frey M, Gierl A. (1997) Biosynthetic origin of oxygen atoms in DIMBOA from maize: NMR studies with 18O2. Phytochemistry, 45, 715-718
  • Frey M, Chomet P, Glawischnig E, Stettner C, Grün S, Winklmair A, Eisenreich W, Bacher A, Meeley R, Briggs SP, Simcox K, Gierl A. (1997) Analysis of a chemical plant defense mechanism in grasses. Science, 277, 696-699

Kontakt

Professur Mikrobielle Biotechnologie

Uferstraße 53
D-94315 Straubing

Leitung

Prof. Dr. Bastian Blombach

Tel.: +49 (0) 9421 187-420
Mail: bastian.blombach@tum.de

Sekretariat

Nancy Stüpfert

Tel.: +49 (0) 9421 187-425
Mail: nancy.stuepfert@tum.de